[Sarah Wragg]

Hi allI have found out I am positive for the gene Kir AA through my Spanish clinic. Complex area but may explain my miscarriages and difficulty getting pregnant over last 3 years. We are going for donor eggs in Spain now. It’s a bit similar to NKC issues however I am normal for that test. My clinic in Spain now have to find a donor with specific genes (HLA11) so that my body doesn’t reject the embryo and also less chance of pre eclampsia with this type of embryo gene (another risk for me carrying this AA Kir gene)Feeling rather blurgh about it but have read a lot.Has anyone else found out they have this gene AA Kir? If so how did you get on?Was it natural pregnancy or donor? Do you have any good areas to read about as I’m just getting my head around the HLA concept too ?thanks very much I appreciate it if so x

[Fran]

Hi SarahLou,

I can imagine that this is a lot to take in – and its not an area that is that common – especially in the UK. Is there an option to look at having treatment with immunoglobulins? Some clinics do offer that in form of something called IVIG for immune conditions? Its a little controversial in the UK as the evidence is limited – but in places like the US, its offered routinely.

You may have already seen information like this but Mr Amin Gorgy has studied reproductive immunolgy for many years and he has some useful information on his website about it. The IVFN is not affiliated with Mr Gorgy or his clinic but I thought it might be worth sharing the information in case you find it useful.

https://www.fertility-academy.co.uk/treatments/reproductive-immunology/

Let me know if you have any questions.

Fran

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